Sreerama Shetty Selected Research

Urokinase-Type Plasminogen Activator (Urokinase)

5/2017	p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis.
3/2015	Role of p53-fibrinolytic system cross-talk in the regulation of quartz-induced lung injury.
1/2015	Role of the urokinase-fibrinolytic system in epithelial-mesenchymal transition during lung injury.
7/2013	Regulation of lung injury and fibrosis by p53-mediated changes in urokinase and plasminogen activator inhibitor-1.
6/2010	Induction of tissue factor by urokinase in lung epithelial cells and in the lungs.
2/2010	Urokinase receptor expression involves tyrosine phosphorylation of phosphoglycerate kinase.
2/2009	Post-transcriptional regulation of urokinase-type plasminogen activator receptor expression in lipopolysaccharide-induced acute lung injury.
9/2008	Urokinase expression by tumor suppressor protein p53: a novel role in mRNA turnover.
10/2006	Urokinase induces activation of STAT3 in lung epithelial cells.
4/2005	Regulation of urokinase receptor mRNA stability by hnRNP C in lung epithelial cells.

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Sreerama Shetty Research Topics

Disease

16	Lung Injury 11/2023 - 05/2003
9	Pulmonary Fibrosis (Fibrosing Alveolitis) 03/2022 - 12/2008
9	Pneumonia (Pneumonitis) 01/2019 - 08/2002
6	Acute Lung Injury 01/2019 - 12/2008
6	Neoplasms (Cancer) 09/2010 - 08/2002
5	Endotoxemia 01/2016 - 06/2003
5	Carcinoma (Carcinomatosis) 09/2008 - 07/2004
4	Chronic Obstructive Pulmonary Disease (COPD) 11/2023 - 01/2015
4	Infections 01/2022 - 02/2009
4	Inflammation (Inflammations) 01/2015 - 09/2010
3	Fibrosis (Cirrhosis) 10/2020 - 07/2013
2	Idiopathic Pulmonary Fibrosis 02/2018 - 01/2015
2	Pleural Effusion (Pleural Effusions) 07/2017 - 08/2016
2	Sepsis (Septicemia) 05/2017 - 04/2015
2	Pulmonary Edema 01/2016 - 06/2003
2	Acute Kidney Injury (Acute Renal Failure) 06/2014 - 01/2014
1	Metaplasia 11/2023
1	Cicatrix (Scar) 01/2023
1	Cytokine Release Syndrome 01/2022
1	Hypoxia (Hypoxemia) 10/2020
1	Empyema 07/2017
1	Edema (Dropsy) 08/2016
1	Philadelphia Chromosome 08/2016
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 08/2016
1	Leukemia 08/2016
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 08/2016
1	Respiratory Tract Infections (Respiratory Tract Infection) 03/2016
1	Lung Diseases (Lung Disease) 04/2015
1	Silicosis 03/2015
1	Herpes Zoster 01/2015
1	Septic Shock (Toxic Shock Syndrome) 06/2014
1	Malignant Mesothelioma 09/2010
1	Mesothelioma 09/2010
1	Pathologic Processes 10/2006

Drug/Important Bio-Agent (IBA)

12	Plasminogen Activator Inhibitor 1IBA 11/2023 - 05/2003
12	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 05/2017 - 05/2003
9	Messenger RNA (mRNA)IBA 03/2016 - 01/2004
7	caveolin-1 (82-101)IBA 03/2022 - 01/2015
6	SmokeIBA 11/2023 - 08/2011
6	CytokinesIBA 01/2022 - 06/2003
5	Plasminogen Activators (Plasminogen Activator)IBA 11/2023 - 07/2008
5	Bleomycin (Blenoxane)FDA LinkGeneric 10/2020 - 07/2013
5	EndotoxinsIBA 01/2016 - 02/2009
5	Proteins (Proteins, Gene)FDA Link 03/2011 - 07/2004
5	Urokinase Plasminogen Activator ReceptorsIBA 02/2010 - 05/2003
3	Tumor Suppressor Protein p53IBA 11/2023 - 03/2016
3	Peptides (Polypeptides)IBA 01/2023 - 02/2018
3	InflammasomesIBA 01/2019 - 04/2015
3	Sirtuin 1IBA 05/2017 - 01/2014
3	Carrier Proteins (Binding Protein)IBA 07/2008 - 01/2004
2	Amino Acids FDA Link 11/2023 - 12/2019
2	Caveolin 1IBA 11/2023 - 02/2018
2	AntigensIBA 01/2022 - 01/2015
2	EnzymesIBA 10/2020 - 03/2015
2	Silicon Dioxide (Silica)FDA LinkGeneric 05/2017 - 03/2015
2	CollagenIBA 04/2015 - 01/2015
2	FibrinIBA 03/2012 - 06/2010
2	Tyrosine (L-Tyrosine)FDA Link 03/2011 - 01/2004
1	caveolin-1 scaffolding domain peptide CSP7IBA 11/2023
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	Succinic Acid (Succinate)IBA 10/2020
1	Glucose (Dextrose)FDA LinkGeneric 10/2020
1	Lactic Acid (Lactate)FDA LinkGeneric 10/2020
1	indium-bleomycinIBA 12/2019
1	CAY10603IBA 01/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	Protein CIBA 01/2017
1	Surface-Active Agents (Surfactants)IBA 01/2017
1	Pulmonary Surfactant-Associated Protein CIBA 01/2017
1	amsonic acid (DAS)IBA 08/2016
1	Dasatinib (BMS 354825)FDA Link 08/2016
1	Tyrosine Kinase InhibitorsIBA 08/2016
1	AlbuminsIBA 08/2016
1	CXC ChemokinesIBA 03/2016
1	Interleukin-8B ReceptorsIBA 03/2016
1	CateninsIBA 01/2016
1	tubastatin AIBA 01/2016
1	TubulinIBA 01/2016
1	Phosphotransferases (Kinase)IBA 12/2015
1	src-Family KinasesIBA 12/2015
1	Histone Deacetylases (Histone Deacetylase)IBA 04/2015
1	QuartzIBA 03/2015
1	ChemokinesIBA 03/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2015
1	Plasminogen InactivatorsIBA 01/2015
1	Cadherins (E-Cadherin)IBA 01/2015
1	resolvin D1IBA 06/2014
1	3' Untranslated Regions (3' UTR)IBA 07/2013
1	SerpinsIBA 08/2011
1	3-nitrotyrosineIBA 03/2011
1	Biomarkers (Surrogate Marker)IBA 03/2011
1	monoamine-sulfating phenol sulfotransferaseIBA 03/2011
1	Oxidants (Oxidizing Agents)IBA 03/2011
1	LipopolysaccharidesIBA 02/2009
1	Serine Proteases (Serine Protease)IBA 10/2006
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2003

Therapy/Procedure

1	Therapeutics 07/2017
1	Thrombolytic Therapy 07/2017
1	Punctures 04/2015
1	Ligation 04/2015